Skip to main content

Table 1 Baseline characteristics of patients with pancreatic ductal adenocarcinoma

From: Genetic assessment of pathogenic germline alterations in lysosomal genes among Asian patients with pancreatic ductal adenocarcinoma

Variables

 

Age, years, median (range)

65 (35–87)

Sex, no. (%)

 Male

243 (58.1)

 Female

175 (41.9)

 BMI, kg/m2, median (range)

22.7 (14.3–32.3)

DM, no. (%)

 No

272 (65.1)

 Yes

146 (34.9)

Smoking, no. (%)

 No

296 (70.8)

 Yes

122 (29.2)

Alcohol, no. (%)

 No

278 (66.5)

 Yes

140 (33.5)

 CEA, ng/mL, median (range)

2.4 (0–880)

 CA 19-9, U/mL, median (range)

150.6 (0–140,000)

AJCC 8th stage of cancer, no. (%)

 I

78 (18.7)

 II

123 (29.4)

 III

112 (26.8)

 IV

105 (25.1)

 CPG carrier, no. (%)a,c

15 (3.6)

 LSD gene carrier, no. (%)b,c

34 (8.1)

 Non-carrier, no. (%)

371 (88.7)

  1. SD standard deviation, BMI body mass index, DM diabetes mellitus, CEA carcinoembryonic antigen, CA 19-9 carbohydrate antigen 19-9, AJCC The American Joint Committee on Cancer, CPG cancer predisposition genes, LSD lysosomal storage disease
  2. aGene; CHEK2, BRCA2, COL7A1, BRCA1, ATM, KRAS, TP53
  3. bGene; GALC, HEXB, NPC1, IDUA, PSAP, MAN2B1, GAA, ARSA, HEXA, SGSH, NAGLU, MCOLN1, HYAL1, GUSB, GNPTG
  4. cTwo patients were carriers of both the CPG and LSD genes