Fig. 2
Increased proliferation and profile of differentially expressed genes in KrasG12D/Galc knockout mouse-derived pancreatic organoids. a Heatmap of RNA sequencing showing differentially expressed genes between KrasG12D knockout (KO) organoids and KrasG12D/Galc KO organoids. b and c Proliferation of organoids was visualized using Ki-67, a proliferation marker, using immunofluorescence assay under confocal fluorescence microscope, and the number of Ki-67 was represented in a bar graph. P** < 0.01, P*** < 0.001. d The biological process, cellular components and molecular function were identified from GO enrichment analysis. GO, Gene Ontology