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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Semiautomated pipeline for quantitative analysis of heart histopathology

Fig. 6

TAC experiment capillary density and pro-ANP expression. A Representative images of cross sections of sham and TAC mice, WGA (green), CD31 (red), and DAPI (blue) (scale = 20 µm). B Cardiomyocyte area and MinFeret of sham mice (n = 9) and TAC mice (n = 9) from three cross section images per animal of the inner wall of the left ventricle with manual correction C and their nuclei area and MinFeret with manual correction. D Capillary area and MinFeret of sham mice (n = 9) and TAC mice (n = 9) from three cross section images per animal of the inner wall of the left ventricle with manual correction. E Capillary contacts (CC) of one cardiomyocyte and ratio from CC to the area of the cardiomyocyte (CM). F Representative images of cross sections of sham and TAC mice, WGA (green), pro-ANP (red), and DAPI (blue). (scale = 20 µm). G Pro-ANP expression of sham mice (n = 9) and TAC mice (n = 9) per area of cardiomyocyte (CM) in percent (%) from three cross section images per animal of the inner wall of the left ventricle with manual correction. H Spearman correlation matrix of cardiomyocyte (CM) area, cardiomyocyte MinFeret, cardiomyocyte nuclei area, capillary contacts, Ratio of capillary contacts (CC) and cardiomyocyte area, and pro-ANP expression in percent of cardiomyocyte area

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