Fig. 5

Positive candidates extend the survival of Lmna DCM. (a) Comparison of EF (%) assessed by echocardiography in control and Lmna DCM mice supplemented with potential candidates compared to control (P value in green) or Lmna DCM (P value in black). Echocardiography was performed 3 weeks after transduction, n = 5, Brown-Forsythe and Welch ANOVA test with Dunnett’s T3 correction. (b) Survival curve of Lmna DCM mice supplemented with selected candidates (Red) compared to Lmna DCM mice (Black), n = 10, Log- rank (Mantel- Cox) test