Fig. 5

Cell proliferation of core and edge minipig spinal cord glioma cells in a nude mice xenograft model a Core and edge cells were staining with GFP and mCherry. Scale bar: 50 μm; b Cell proliferation rates of two cell lines were determined by MTT assay for 5 days. c Body weight of nude mice with flank injection of core and edge cells. d Tumor volume curve in nude mice by core and edge cells. e Representative macroscopic images of tumor growth in core and edge nude mice models. f H&E, Ki67, 4-HNE and NQO1 staining of tumor slices in various groups. Scale Bars: 50 μm. Significant differences are considered when *p < 0.05; **p < 0.01. n = 8