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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Tumor microenvironment in a minipig model of spinal cord glioma

Fig. 4

SCG Tumor Edge Exhibits Increased Markers of Oxidative Stress. a Expression of 8-hydroxy-2-deoxyguanosine. b Carbonyl expression levels. c GSH/GSSG ratios. d ATP levels. e LDH ratios. Data are means ± SEM (*p < 0.05; **p < 0.01; ***p < 0.001, n = 4) f Representative immunofluorescent staining of edge and core minipig SCG tissues for 4-HNE (green), Ki67 (red), NQO1 (cyan) and DAPI (blue). Scale bars: 100 μm. n = 4. g HIF-1α, CA-IX, GLUT-1 staining in tumor core and edge of minipig SCG tissues. Scale bars: 100 μm. n = 4

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