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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Tumor microenvironment in a minipig model of spinal cord glioma

Fig. 1

Establishment a Cohort of Minipig SCG and Defining Core and Edge Regions. a Lentiviral vectors expressing PDGFB, HRASG12V, and shRNA targeting P53 (sh787, sh944) were designed based on prior literature. b Schematic representation of the timeline of tumor progression in the spinal cord minipig model. c Representative endpoint MRI of T1w post-contrast demonstrating a contrast enhancing lesion in the oncogene injection site. d Representative H&E staining showing edge and core tumor regions in the spinal cord glioma. Scale bar: 2 mm and 100 μm

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