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Table 2 Comparison of risk calculated from established models between Chinese patients with high versus low risk based on binary risk classification of 70-gene signature test

From: Nomogram prediction of the 70-gene signature (MammaPrint) binary and quartile categorized risk using medical history, imaging features and clinicopathological data among Chinese breast cancer patients

Risk calculated from established models

70-gene high risk N = 62 (%)

70-gene low risk N = 88(%)

P-value

AOL

 High

46 (74.2)

61 (69.3)

0.516

 Low

16 (25.8)

27 (30.7)

CTS5

 Score (Mean ± SD)

3.29 ± 0.58

3.14 ± 0.64

0.137

CTS5

 High

8 (12.9)

12 (13.6)

0.035

 Intermediate

33 (53.2)

29 (33.0)

 Low

21 (33.9)

47 (53.4)

IHC3

 High

27 (43.5)

10 (11.4)

 < 0.001

 Low

35 (56.5)

78 (88.6)

NPI

 Score (Mean ± SD)

4.58 ± 0.49

4.30 ± 0.52

0.001

NPI

 Poor

0 (0.0)

1 (1.1)

0.348^

 Moderate

48 (77.4)

60 (68.2)

 Good

14 (22.6)

27 (30.7)

  1. AOL Adjuvant! Online, CTS5 Clinical treatment Score post–5 years, IHC3, immunohistochemistry 3, NPI Nottingham prognostic index
  2. ^The comparison was performed by fisher test