Skip to main content

Table 1 Clinical characteristics in the CHD patients and Controls (page 8, l. 204)

From: Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD

 

CHD patients

Controls

p value

Age (years)

66.5 (62,71.8)

69 (63, 71.5)

 

Male (%)

40 (76.9%)

11 (50%)

0.04

Smoker (previous/current)

31 (59.6%)

10 (45.5%)

 

Weight (Kg)

85 (70.3, 95.5)

82.5 (77.5, 107.0)

 

Height (m)

1.77 (1.68, 1.81)

1.75 (1.67, 1.82)

 

Waist (cm)

92 (86, 98)

90 (88, 101)

 

BMI (kg/m2)

27.3 (23.8, 30.1)

28.4 (24.6, 31.6)

 

SBP (mmHg)

140 (125, 160)

140 (115, 163)

 

DBP (mmHg)

80 (70, 87)

79 (70, 86)

 

Cardiovascular status

 Previous AMI (%)

20 (38.5%)

2 (9.1%)

0.025

 Angina (%)

24 (46.2%)

0 (0%)

 < 0.001

 PCI (%)

20 (38.5%)

0 (0%)

0.002

 Hypertension (%)

28 (53.9%)

9 (40.9%)

 

 Diabetes type I and II (%)

14 (26.9%)

3 (13.6%)

 

 Heart failure (%)

3 (5.8%)

1 (4.5%)

 

Medications

 Aspirin (%)

45 (86.5%)

9 (40.9%)

 < 0.001

 Other antiplatelet (%)

14 (26.9%)

0 (0%)

 

 ACEi/ATII (%)

24 (46.2%)

11 (50%)

 

 Beta-blockers (%)

32 (61.5%)

6 (27.3%)

0.015

 Statins (%)

37 (71.2%)

11 (50%)

 

 Other lipid-lowering agents (%)

10 (19.2%)

1 (4.5%)

 

 Insulin (%)

6 (11.5%)

0 (0%)

 

 Anti-diabetic drugs (%)

11 (21.2%)

3 (13.6%)

 

 Diuretics (%)

7 (13.5%)

5 (22.7%)

 

Laboratory values

 hsCRP (mg/L)

0.91 (0.49, 1.77)

1.00 (1.00, 2.00)

 

 Troponin T (ng/L)

13 (9, 22)

11.5 (9, 25)

 

 TC (mmol/L)

3.1 (2.7, 3.4)

3.9 (2.8, 4.6)

0.026

 HDL-C (mmol/L)

0.97 (0.75, 1.12)

1.10 (0.87, 1.30)

 

 LDL-C (mmol/L)

1.83 (1.4, 2.2)

2.18 (1.8, 2.9)

0.02

 Triglycerides (mmol/L)

1.22 (1.0, 1.8)

1.02 (0.9, 1.7)

 

 Glucose (mmol/L)

5.6 (4.9, 6.6)

5.6 (4.9, 6.3)

 

 HbA1c (mmol/mol)

39 (36, 51)

36 (33, 38)

0.011

 GFR (%)

90 (75, 95)

80 (68, 91)

0.03

 Creatinine (μmol/L)

76 (67, 85)

80 (64.8, 91)

 

 Uric acid (μmol/L)

313 (271, 362)

317 (258, 396)

 
  1. Levels are median (25, 75 percentiles) or number (% frequency). P-values < 0.05 are shown
  2. BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, AMI Acute Myocardial Infarction, PCI Percutaneous Coronary Intervention, ACEi Angiotensin-Converting Enzyme inhibitors, ATII Angiotensin II receptor antagonist, NSAIDs non-steroidal anti-inflammatory drugs, hsCRP high sensitive C-reactive protein, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, HbA1C glycosylated haemoglobin A1c, GFR Glomerular filtration rate