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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL data

Fig. 2

Genetic variations and expression of MRGs in IA blood samples. A PCA for combined expression profile before and after ComBat. B At the blood level, principal component analysis separates normal (grey), RIA (yellow) and UIA samples (blue). Heat map (C) and box plot (D) showing 19 MRGs differentially expressed in normal, RIA and UIA blood. *p < 0.05; **p < 0.01; ***p < 0.001; ns no statistical significance

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