Fig. 9

The evaluation of high- and low-risk groups in TME. A The stromal score, immune score, and ESTIMATE score of the two groups (high-risk group: n = 152; low-risk group, n = 152). B The heat map exhibited the difference between high- and low-risk groups in the hub genes involved in the three features. Differences in TIICs enrichment performed by two algorithms, including XCELL (C) and CIBERSORT (D). E The expression levels of immune checkpoints between high- and low-risk groups. The ssGSEA score (F) and immunogram radar plot (G) displayed the association between two groups and TME signatures constructed by Kobayash. The ssGSEA score (H) and immunogram radar plot (I) displayed the association between two groups and TME signatures constructed by Bagaev. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns: nonsignificant