Fig. 10

Identification of genetic mutations underlying the risk model. The waterfall plots of the high-risk group (n = 144, A) and low-risk group (n = 142, B) in the TCGA cohort. C Top 5 frequently mutated genes in high- and low-risk groups. Gene mutations in the PI3K-MAPK (D) and TGFβ (E) pathways. F Focal peaks showed CNV types: red (amplification) and blue (deletion). G The incidence of amplification or deletion of genomic regions in the high- and low-risk groups. CNV copy number variation. *p < 0.05; **p < 0.01