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Table 2 Association of SII with Metabolic syndrome (MetS) and its components

From: Association between systemic immune-inflammation index and metabolic syndrome and its components: results from the National Health and Nutrition Examination Survey 2011–2016

 

Crude model

Model 1

Model 2

 

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

P value

MetS

      

Continous Lg-SII

1.85 (1.47,2.34)

 < 0.001

1.65 (1.29,2.11)

 < 0.001

1.44 (1.12,1.84)

0.006

 Quartile 1

Ref.

 

Ref.

 

Ref.

 

 Quartile 2

1.20 (1.06,1.36)

0.005

1.18 (1.04,1.34)

0.010

1.16 (1.02,1.33)

0.027

 Quartile 3

1.35 (1.19,1.52)

 < 0.001

1.29 (1.14,1.47)

 < 0.001

1.25 (1.10,1.43)

0.002

 Quartile 4

1.52 (1.33,1.74)

 < 0.001

1.43 (1.23,1.66)

 < 0.001

1.33 (1.14,1.55)

 < 0.001

 P for trend

 < 0.001

 

 < 0.001

 

 < 0.001

 

Elevated FPG

      

Continous Lg-SII

1.36 (1.08,1.71)

0.010

1.28 (1.02,1.60)

0.034

1.14 (0.89,1.46)

0.275

 Quartile 1

Ref,

 

Ref,

 

Ref,

 

 Quartile 2

1.01 (0.87,1.16)

0.948

1.00 (0.86,1.17)

1.000

0.99 (0.84,1.17)

0.904

 Quartile 3

1.05 (0.91,1.21)

0.533

1.04 (0.89,1.21)

0.629

1.01 (0.86,1.19)

0.896

 Quartile 4

1.23 (1.07,1.41)

0.004

1.19 (1.03,1.38)

0.023

1.12 (0.96,1.31)

0.153

 P for trend

0.005

 

0.022

 

0.136

 

Low HDL-C

      

Continous Lg-SII

1.50 (1.18,1.91)

0.001

1.43 (1.11,1.84)

0.007

1.29 (0.99,1.67)

0.056

 Quartile 1

Ref,

 

Ref,

 

Ref,

 

 Quartile 2

1.09 (0.94,1.27)

0.251

1.07 (0.92,1.25)

0.382

1.04 (0.88,1.23)

0.607

 Quartile 3

1.18 (1.01,1.38)

0.043

1.14 (0.97,1.34)

0.120

1.11 (0.94,1.31)

0.213

 Quartile 4

1.30 (1.12,1.50)

 < 0.001

1.26 (1.08,1.46)

0.003

1.17 (1.00,1.38)

0.047

 P for trend

 < 0.001

 

0.003

 

0.038

 

Elevated TG

      

Continous Lg-SII

1.44 (1.15,1.81)

0.002

1.28 (1.01,1.63)

0.044

1.15 (0.91,1.46)

0.241

 Quartile 1

Ref.

 

Ref.

 

Ref.

 

 Quartile 2

1.14 (0.98,1.31)

0.083

1.07 (0.93,1.25)

0.341

1.05 (0.90,1.23)

0.494

 Quartile 3

1.20 (1.03,1.39)

0.021

1.11 (0.95,1.31)

0.196

1.08 (0.91,1.27)

0.375

 Quartile 4

1.24 (1.08,1.42)

0.003

1.16 (0.10,1.36)

0.052

1.09 (0.93,1.28)

0.265

 P for trend

0.003

 

0.052

 

0.264

 

 Elevated WC

      

Continous Lg-SII

2.76 (2.12,3.60)

 < 0.001

2.40 (1.82,3.17)

 < 0.001

2.17 (1.65,2.87)

 < 0.001

 Quartile 1

Ref.

 

Ref.

 

Ref.

 

 Quartile 2

1.30 (1.13,1.51)

 < 0.001

1.32 (1.12,1.54)

0.001

1.31 (1.11,1.53)

0.002

 Quartile 3

1.64 (1.40,1.91)

 < 0.001

1.62 (1.37,1.91)

 < 0.001

1.56 (1.33,1.83)

 < 0.001

 Quartile 4

1.86 (1.60,2.17)

 < 0.001

1.69 (1.44,1.99)

 < 0.001

1.59 (1.35,1.87)

 < 0.001

 P for trend

 < 0.001

 

 < 0.001

 

 < 0.001

 

 Elevated BP

      

Continous Lg-SII

1.61 (1.17,2.20)

0.004

1.74 (1.28,2.37)

 < 0.001

1.65 (1.20,2.27)

0.003

 Quartile 1

Ref.

 

Ref.

 

Ref.

 

 Quartile 2

1.10 (0.89,1.36)

0.360

1.19 (0.96,1.47)

0.105

1.19 (0.96,1.48)

0.110

 Quartile 3

1.36 (1.15,1.62)

 < 0.001

1.48 (1.25,1.76)

 < 0.001

1.46 (1.24,1.72)

 < 0.001

 Quartile 4

1.38 (1.13,1.69)

0.003

1.47 (1.21,1.80)

 < 0.001

1.44 (1.18,1.75)

0.001

 P for trend

 < 0.001

 

 < 0.001

 

 < 0.001

 
  1. Crude Model: There are no covariates were adjusted
  2. Model 1: Age, sex, and race/ethnicity were adjusted
  3. Model 2: Age, sex, race/ethnicity, education levels, poverty income ratio, marital status, use of medication, history of cancer , family history of diabetes, smoking status, physical activity, and alcohol consumption were adjusted
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Journal of Translational Medicine

ISSN: 1479-5876

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