Table 2 Associations between change patterns in the 5-year ASCVD risk status and subsequent ASCVD incidence
Events/Total | Unadjusted model | Multivariable model 1a | Multivariable model 2b | ||||
|---|---|---|---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | HR (95% CI) | p value | ||
ASCVD risk change group (with consistently high as the reference) | |||||||
Consistently High | 519/1539 | 1 (Reference) | / | 1 (Reference) | / | 1 (Reference) | / |
Non-high to High | 681/2230 | 0.66 (0.59–0.74) | < 0.01 | 0.66 (0.59–0.75) | < 0.01 | 0.67 (0.59–0.77) | < 0.01 |
High to non-high | 51/221 | 0.62 (0.46–0.82) | < 0.01 | 0.63 (0.46–0.85) | < 0.01 | 0.57 (0.41–0.80) | < 0.01 |
Consistently non-high | 1309/7036 | 0.31 (0.28–0.35) | < 0.01 | 0.32 (0.29–0.36) | < 0.01 | 0.33 (0.29–0.37) | < 0.01 |
ASCVD risk change group (with consistently non-high as the reference) | |||||||
Consistently non-high | 1309/7036 | 1 (Reference) | / | 1 (Reference) | / | 1 (Reference) | / |
High to non-high | 51/221 | 1.97 (1.49–2.61) | < 0.01 | 1.94 (1.45–2.61) | < 0.01 | 1.74 (1.26–2.41) | < 0.01 |
Non-high to high | 681/2230 | 2.11 (1.93–2.33) | < 0.01 | 2.05 (1.86–2.26) | < 0.01 | 2.04 (1.84–2.27) | < 0.01 |
Consistently high | 519/1539 | 3.19 (2.88–3.54) | < 0.01 | 3.09 (2.77–3.44) | < 0.01 | 3.03 (2.69–3.42) | < 0.01 |