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Table 2 The diagnostic efficacy evaluation of CSF NGAL for acute BM

From: Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study

CSF NGA L

AUC-ROC (95%CI)

Cutoff (ng/mL)

Sensitivity (95% CI)

Specificity (95% CI)

P value

BM vs.TBM

0.812 (0.723–0.876)

64.24

74.14 (62.5–84.5)

74.14 (61.0–84.7)

 < 0.001

BM vs.CM

0.724 (0.587–0.861)

65. 23

74.36 (64.5–84.5)

80.39 (66.9–90.2)

 < 0.001

BM vs.TBM + CM

0.834 (0.770–0.886)

74.27

70.15 (57.7–80.7)

77.36 (68.2–84.9)

 < 0.001

  1. BM bacterial meningitis, AUC area under the curve, ROC receiver operating characteristic curve, NGAL Neutrophil Gelatinase-Associated Lipocalin, CI confidence interval