Table 1 Clinical characteristics and common laboratory tests of the study subjects
Characteristics | BM (n = 67) | TBM (n = 55) | CM (n = 51) | HC (n = 58) | P value |
|---|---|---|---|---|---|
Age, median(range) | 43 (0.8–84) | 48 (27–80) | 41 (14–73) | 48 (22–81) | 0.093 |
Male, n (%) | 44 (65.7) | 38 (69.1) | 37 (72.5) | 34 (58.6) | 0.336 |
Fever, n (%) | 49 (73.1) | 47 (85.4) | 34 (66.7) | – | 0.271 |
Headache, n (%) | 56 (83.6) | 51 (92.7) | 51 (100) | – | 0.355 |
Vomiting, n (%) | 20 (29.8) | 13 (23.6) | 12 (23.5) | – | 0.833 |
Altered consciousness, n (%) | 11 (16.4) | 7 (12.7) | 8 (15.6) | – | 0.856 |
Meningeal irritation, n (%) | 41 (61.2) | 39 (70.9) | 29 (56.8) | – | 0.279 |
IP (mmH2O), median (IQR) | 230 (103,350) | 190 (60,330) | 270 (165,360) | 157 (50,220) | 0.402 |
CSF smear/culture, n (%) | 9 (13.4) | 1 (1.8) | 37 (72.5)†| – |  < 0.001 |
ATBA n (%) | 58 (86.6) | 40 (72.7) | 36 (70.6) | 21 (63.6) | 0.784 |
CSF, median (IQR) | |||||
 WBC(× 106/L) | 228 (90,1977) | 173 (65,425) | 107 (54,176) | 3.7 (3.0,6.0) |  < 0.001 |
 Chloride(m mol/L) | 114 (112,118) | 113 (108,120) | 115 (109,121) | 121 (119,123) | 0.011 |
 Glucose(m mol/L) | 2.58 (2.01,3.02) | 2.43 (1.93,2.62) | 2.46 (1.91,2.66) | 2.98 (2.65,3.49) | 0.001 |
 Protein(g/L) | 1.42 (0.88,2.93) | 1.38 (0.72,2.13) | 1.23 (0.73,1.80) | 0.41 (0.30,0.51) |  < 0.001 |
Serum, median (IQR) | |||||
 WBC (× 109/L) | 11.4 (4.5,21.2) | 8.7 (5.1,14.7) | 10.7 (8.6,16.8) | 7.6 (3.8,18.7) | 0.039 |
 CRP (g/L) | 108.2 (2.6,401) | 74.5 (1.9,253) | 113.6 (5.0,330) | 56.6 (2.2,160) | 0.351 |