Table 2 Internal validity of included studies
From: Cell-therapy for Parkinson’s disease: a systematic review and meta-analysis
Study | Prospective design | Multicenter enrollment | Selection bias | Performance bias | Attrition bias | Detection bias | Multivariate adjustment for potential confounders |
|---|---|---|---|---|---|---|---|
Schiess 2021 [102] | Yes | No | D | B | A | D | Probably adequate |
Venkataramana 2012 [103] | Yes | No | D | B | C | A | Probably adequate |
Boika 2020 [104] | Yes | No | D | B | A | D | Probably adequate |
Storch 2012 [105] | No | Yes | D | D | C | D | Not reported |
Brazzini 2010 [106] | No | No | D | B | A | C | Not reported |
Madrazo 2019 [107] | Yes | No | D | B | A | D | Probably adequate |
Lige 2016 [108] | Yes | No | D | B | A | D | Not reported |
Sinelnyk 2015 [109] | Yes | No | D | B | A | D | Probably adequate |
Yin 2012 [110] | Yes | No | D | B | A | A | Probably adequate |
Gross 2011 [111] | Yes | Yes | A | A | A | A | Probably adequate |
Stover 2005 [112] | Yes | No | D | B | A | D | Probably adequate |