Fig. 6
From: The application of HER2 and CD47 CAR-macrophage in ovarian cancer
Outline diagram of the anti-tumor mechanism of HER2/CD47 CAR-M. The CAR gene was introduced into macrophages by viral transfection to obtain CAR-expressing CAR-M, HER2/CD47 CAR-M inhibits ovarian cancer growth and proliferation by phagocytosis both in vitro and in vivo, promoting adaptive immunity and influencing the tumor microenvironment (created with BioRender.com).