Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia

Table 3 Antibody profile in first-trimester serum

Antibody (g/L)	Control (N = 34)	PE (N = 34)	P value
Total Igs (g/L)
*Total IgA	0.41 ± 0.06	0.33 ± 0.09	< 0.001
*Total IgM	32.98 ± 5.47	40.50 ± 2.65	< 0.001
*Total IgG	10.27 ± 1.30	12.06 ± 1.10	< 0.001
aPS Antibodies (OD values at 450 nm)
aPS IgA	0.72 ± 0.17	0.71 ± 0.15	0.879
aPS IgM	0.70 ± 0.21	0.71 ± 0.19	0.969
*aPS IgG	0.19 (0.14, 0.25)	0.33 (0.21, 0.42)	< 0.001
aPS-IgA IC	0.60 ± 0.18	0.57 ± 0.15	0.423
aPS-IgM IC	0.59 ± 0.21	0.60 ± 0.14	0.842
*aPS-IgG IC	1.63 ± 0.28	1.77 ± 0.27	0.035

Data are presented as the mean ± standard deviation and median (interquartile range). P < 0.05 was considered statistically significant and indicated by an asterisk
Ig immunoglobulin, aPS anti-phosphatidylserine, OD optical density, IC immune complex

ISSN: 1479-5876