Fig. 5

IFI6 promotes the growth and proliferation of RS4;11 cells in vivo. A Schematic diagram of subcutaneous tumor formation in mice. B The size of subcutaneous tumors in the RS4;11 injection group, RS4;11 + MSCs injection group, RS4;11 + MSCs-EV injection group, and RS4;11 + MSCs-LV-IFI6 injection group, n = 3. C Average tumor weight in each group was calculated at 25 days after injection. mean ± SD. *P < 0.05, **P < 0.01. D Average tumor volume in each group was evaluated at 25 days after injection. mean ± SD. *P < 0.05. E HE staining (200 ×) of tumor tissue in each group (scale bars, 50 µm). F The expression of IFI6 (400 ×) and Ki-67 (400 ×) in xenotransplanted tumors in each group with immunohistochemical staining (scale bars, 20 µm)