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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6

Fig. 3

The gene expression profiling datas were been screened. A and B The volcano plots of gene expression in GSE101454 dataset (A) and this study (B) based on -log10 (P value) (MSCs in co-culture vs MSCs in mono-culture). C Venn diagram for differentially expressed genes visualization in GSE101454 dataset and this study. D and E The expression levels of IFI6, IFI44L, IFIT1, IFIT3, IFITM1, ISG15 and MX1 in MSCs cultured alone group and MSCs co-cultured with Nalm-6 (D) or RS4;11 (E) group for 72 h by qRT-PCR. Each value indicated three or more independent experiments. *P < 0.05, **P < 0.01

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