Fig. 4

A Somatic CNA frequency of individual genes in each group plotted along the chromosomes (upper), comparisons of somatic CNA between BSE and NSE groups with − log10 FDR (Fishers exact test, lower). B The significant copy number variation affects the IFN-λ related network. C ROC curves of the risk score for predicting 1 year, 3 year, and 5 year survival. D Kaplan–Meier survival curves of OS of patients in the low- and high-risk groups in the training set. E Univariate and multivariate analyses of the clinical characteristics and risk score with the OS. F Kaplan–Meier showed the independent relevance between overall survival time and risk scores in the training set. G The ROC curve of the model. H Volcano plot showing the differentially upregulated and downregulated genes. I Bar plot showing the results of GO enrichment and KEGG by the differentially genes