Fig. 5

CCL2 antagonization reversed macrophage polarization and pulmonary fibrosis. A The macrophages polarization of lung tissues with or without Bindarit treatment on 0, 4, 8, 12, 24 weeks after irradiation in RILI mice model by flow cytometry (n = 6). B The protein levels of pulmonary fibrosis markers with or without Bindarit treatment in RILI mice model. C The H&E staining of lung tissues with or without Bindarit treatment in RILI mice model (n = 6). Scale bars: 100 µm (20 × magnification). D The Masson`s trichrome staining of lung tissues with or without Bindarit treatment in RILI mice model (n = 6). Scale bars: 100 µm (20 × magnification).