Fig. 2

Macrophages are polarized upon STING signaling activation in RILI mice model. A The population of macrophages of lung tissues on 0, 4, 8, 12, 24 weeks after irradiation in RILI mice model(n = 6) B The macrophages polarization of lung tissues on 0, 4, 8, 12, 24 weeks after irradiation in RILI mice model by flow cytometry (n = 6). C The correlation between the population of macrophages and the activity of the STING signaling pathway. D The correlation between the macrophages M1 polarization percentage and the activity of the STING signaling pathway. E The correlation between the population of macrophage and the severity of RILI. F The correlation between the macrophages M1 polarization percentage and the severity of RILI. Error bars represent mean ± SD. Statistical analyses were performed using two-tailed Students t-test or one-way ANOVA if more than two groups. ****P < 0.0001