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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice

Fig. 4

a–e BV/TV (%) (a), bone surface density (1/mm) (b), trabecular thickness (mm) (c), trabecular separation (mm) (d) and trabecular number (1/mm) (e) of the callus tissue of controls (white bars, n = 8 at 2 and 5 weeks, n = 10 at 10 weeks) and sildenafil-treated mice (black bars, n = 8 at 2 and 5 weeks, n = 10 at 10 weeks) at 2, 5 and 10 weeks after surgery, as assessed by µCT analysis. Mean ± SEM; *p < 0.05 vs. control

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