Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice

Fig. 2

a–r Representative images of B-mode, hemoglobin oxygen saturation (sO2) and total hemoglobin (HbT) in controls and sildenafil-treated animals at 2 (a–f), 5 (g–l) and 10 weeks (m–r) after surgery. The callus tissue is marked by yellow broken lines. Scale bars:1.5 mm. s sO2 (%) within the callus tissue of controls (white bars, n = 5 at 2, 5 and 10 weeks) and sildenafil-treated animals (black bars, n = 5 at 2, 5 and 10 weeks). t HbT/volume (1/mm³) within the callus tissue of controls (white bars, n = 5 at 2, 5 and 10 weeks) and sildenafil-treated animals (black bars, n = 5 at 2, 5 and 10 weeks). Mean ± SEM; *p < 0.05 vs. control

Back to article page