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Table 4 Validation on retrospective HNSCC cohort of the DKTK-ROG that received primary RCTx. Multivariable Cox regression for loco-regional control

From: Prognostic biomarkers for the response to the radiosensitizer nimorazole combined with RCTx: a pre-clinical trial in HNSCC xenografts

Loco-regional control

Parameter

HR

[95% CI]

p

p16 [negative vs positive]

3.44

[1.06, 11.24]

*0.0405

ln(GTV)

1.31

[0.94, 1.83]

0.1116

N stage [ordinal N0 to N3]

1.12

[0.95, 1.33]

0.1732

DEG [high vs low]

1.81

[1.00, 3.26]

*0.0499

  1. HR hazard ratio, 95% CI 95% confidence interval
  2. N stage ranging from N0 to N3, p values considered as statistically significant are marked with an asterisk *