Fig. 5

Agomir-125a-5p downregulates the proportion of Th17 cells in peripheral blood of IMQ-induced psoriasis-like mice. The proportion of CD25⁺ Foxp3⁺ T cells in peripheral blood of mice from each group by flow cytometry (n = 3, p < 0.01). The proportion of CD4⁺ IL17 ⁺ T cells in peripheral blood of mice from each group by flow cytometry (n = 3, p < 0.05). Data are representative of at least two independent experiments (mean ± SEM). *P < 0.05, **P < 0.01. Two-tailed unpaired Student’s t-test (a, b). miR microRNA; agomir-NC negative control agomir; Con control; IMQ imiquimod; Foxp3 Fork head transcription factor3; IL interleukin