Fig. 6

Association between circulating C18:1AC concentration and AF risk. a Association between acyl-carnitine (AC) serum concentration and atrial fibrillation (AF) risk over time analysed in the overall BiomarCaRE case-cohort set consisting of four different community-based cohorts (DanMONICA, FINRISK97, Moli-sani, SHHEC). Cox regression analyses were performed for each study centre, adjusted for multiple cardiovascular risk factors. Hazard ratios (HRs) and 95-percent confidence interval (95% CI) of the association between C18:1AC serum concentration and AF development shown for each cohort study. HRs are reported for 1 standard deviation (SD) increase. b Kaplan–Meier curve of AF free probability over time depending on C18:1AC serum concentration assessed in the BiomarCaRE case-cohort set