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Table 2 Clinical, biological and hemodynamic data in each of the groups characterized by their level of GFRs

From: Influence of arterial blood gases on the renal arterial resistive index in intensive care unit

 

Normal GFR

n = 35

ARC

n = 17

Kidney failure

n = 12

p

 

Median

CI 95%

Median

CI 95%

Median

CI 95%

 

Age (years)

60

52–68

28

22–48

77.5

57–84.5

0.00001*

Albuminemia (g/L)

24

18.6–27

23

19.5–27

17.6

NA

0.548187

BMI (kg/m2)

25

24–27

25

23–28

28

24.4–31

0.19521

SAPS 2

55

43–64

48

32–53

47

42–64.9

0.34085

SOFA Score

5.5

4–8

6

4–8

4

2.2–4

0.08673

Delay between ICU admission and inclusion (days)

4

3–6.5

4

3–6

12

4–15

0.08731

PEEP (cmH2O)

6

5–7

6

5–8

6

0–8

0.71223

Plasma creatinine (µmol/L)

58

49–69

56

47–64

141

76–182

0.00004*

BUN (mmol/L)

6.2

5.3–8.2

5.4

3.5–7

17.7

7.2–28

0.00177*

CKD-EPI (mL/min/1.73 m2)

104.56

95.9–111

127.4

122.6–137.4

39.98

25–94.3

< 0.000001*

Measured creatinine clearance (mL/min/1.73 m2)

115.83

105–126

204

160.3–265.2

33

23–43.5

< 0.000001*

pH

7.43

7.42–7.45

7.43

7.41–7.46

7.4

7.34–7.47

0.64280

PaO2 (mmHg)

82.2

71–102

85.7

71–111

81.6

69.8–108.3

0.89991

SaO2 (%)

96.4

95–98

97.8

95–98.5

97.2

94–99

0.94325

PaCO2 (mmHg)

37.2

35.9–40

39.4

32.2–41.2

35.9

32.6–45.8

0.71234

Plasma total CO2 content (mmol/L)

25.5

24.9–27

25.6

24.4–27

24

20.4–26.4

0.41107

Hemoglobin (g/dL)

10.1

9.5–10.5

10.2

9.3–11.4

10.2

8.9–12.4

0.90643

SAP (mmHg)

127

119–134

138

130–149

130

122–152

0.09584

DAP (mmHg)

64

58–68

71

64–81

62

50–74

0.08861

MAP (mmHg)

84

80–87.8

90

85–95

84

72–94

0.08589

Pulse pressure (mmHg)

65

56.5–68

66

53–84

69.5

59.9–84

0.42530

Heart rate (bpm)

88

84–94

90

80–112

86

76–102

0.76239

Resistivity Index

0.71

0.66–0.73

0.62

0.596–0.69

0.76

0.69–0.81

0.00533*

Cause of admission

   

0.0001*

Polytrauma

6 (17.1%)

12 (70.6%))

0 (0%)

Surgical

10 (28.6%)

4 (23.5%)

4 (33.3%)

Medical

19 (54.3%)

1 (5.9%)

8 (66.7%)

Sex F/M

13 (37.1%) / 22 (62.9%)

3 (17.6%) / 14 (82.4%)

3 (25%) / 9 (75%)

0.3265

  1. Normal GFR (glomerular filtration rate): measured CLCR between 60 and 150 mL/min/1.73 m2 (for female) and 160 mL/min/1.73 m2 (for male)
  2. ARC (Augmented Renal Clearance): measured CLCR > 150 (for female) et 160 (for male) mL/min/1.73 m2
  3. Kidney failure: Measured CLCR < 60 mL/min/1.73 m2
  4. BMI body mass index, BUN blood urea nitrogen, CI confidence interval, DAP diastolic arterial pressure, ICU intensive care unit, MAP mean arterial pressure, NA not applicable, PEEP positive end-expiratory pressure, SAP systolic arterial pressure, SAPS Simplified Acute Physiology Score, SOFA score Sepsis-related Organ Failure Assessment score
  5. *Statistically significant
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Journal of Translational Medicine

ISSN: 1479-5876

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