Predictive performance of triglyceride glucose index (TyG index) to identify glucose status conversion: a 5-year longitudinal cohort study in Chinese pre-diabetes people

Table 5 Relationship between TyG and normoglycemic conversion in different sensitivity analyses

Exposure	Model I (HR, 95% CI, P)	Model II (HR, 95% CI, P)	Model III (HR, 95% CI, P)	Model IV (HR, 95% CI, P)
TyG	0.918 (0.876, 0.961) 0.00030	0.859 (0.802, 0.920) 0.00001	0.897 (0.839, 0.959) 0.00138	0.917 (0.883, 0.951) < 0.00001
TyG quartile
Q1	1.0	1.0	1.0	1.0
Q2	0.980 (0.923, 1.040) 0.50080	1.025 (0.924, 1.137) 0.63880	0.936 (0.843, 1.040) 0.21861	1.010 (0.959, 1.063) 0.71689
Q3	0.955 (0.890, 1.024) 0.19730	0.972 (0.871, 1.084) 0.60592	0.912 (0.817, 1.017) 0.09665	0.992 (0.938, 1.050) 0.79377
Q4	0.848 (0.781, 0.921) 0.00010	0.782 (0.695, 0.879) 0.00004	0.843 (0.752, 0.945) 0.00344	0.863 (0.810, 0.919) < 0.00001
P for trend	0.00039	0.00003	0.00369	0.00002

Model I was a sensitivity analysis performed after excluding participants with BMI ≥ 25 kg/m2. we adjusted age, sex, SBP, DBP, ALT, AST, BUN, LDL-C, HDL-c, Scr,family history of diabetes, drinking status, and smoking status
Model II was a sensitivity analysis performed on participants who had never consumed alcohol. we adjusted age, sex, BMI, SBP, DBP, ALT, AST, BUN, LDL-C, HDL-c, Scr, family history of diabetes, and smoking status
Model III was a sensitivity analysis performed on participants who had never smoked. we adjusted age, sex, BMI, SBP, DBP, ALT, AST, BUN, LDL-C, HDL-c, Scr, family history of diabetes, and drinking status
Model IV was a sensitivity analysis performed on participants without a family history of diabetes. we adjusted age, sex, BMI, SBP, DBP, ALT, AST, BUN, LDL-C, HDL-c, Scr, smoking status, and drinking status
HR Hazard ratios, CI confidence

ISSN: 1479-5876