Fig. 8From: JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cellsMechanism graph of the regulatory network. The JMJD6–BRD4 complex elevates the expression of ERK2 (MAPK1) through the HOTAIR-LSD1 axis, thereby maintaining the stemness of LCSCs and enhancing their radioresistanceBack to article page