Fig. 5

Upregulated genes in neoplastic tissue compartments in relapsed patients in comparison to non-relapsed patients (N = 10). a Volcano plot with a significance level α = 0.05 of significantly upregulated genes in the neoplastic tissues compartment of relapsed patients in comparison to non-relapsed patients. b–d The expression level of OTOP2, FGFR and MMP11 in relapsed patients (orange) indicated a significant increase in comparison to non-relapsed patients (green). Significant differences (*p < 0.05 and **p < 0.005) were highlighted with bars and asterisks