Methods of ex vivo analysis of tissue status in vascularized composite allografts

Table 2 A comparison of clinically relevant features of VCA assessment modalities

Technique	Non-destructive	Portable	Rapid	Continuous	High Res	Quantitative	Facile analysis	Low cost	Refs.
Histology	○	○	○	○	•	○	•	•	[55, 200]
Wet:dry weight	○	•	○	○	○	•	•	•	[105, 201]
Optical 3D scanning	•	•	•	○	○	•	•	•	[150, 202]
OCT	•	○	○	○	•	○	○	○	[145]
Laser Doppler imaging	•	•	•	•	○	◒	○	•
Thermographic imaging	•	•	•	•	○	•	•	•	[138,139,140, 143]
NIR lymph-angiography	•	○	•	•	•	◒	•	○	[146, 149]
X-ray	◒	•	•	○	○	○	○	•	[144]
CT and µCT	◒	○	○	○	•	◒	○	○	[144, 155, 156, 181]
fMRI	•	○	○	○	•	◒	○	○	[160, 162, 163]
Ultrasound	•	•	•	○	•	◒	•	•	[170, 171, 173, 174]
Bioimpedance spectroscopy	•	•	•	•	◒	•	◒	•	[184, 195, 203]

ISSN: 1479-5876