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Table 1 A summary of the data for Mendelian randomization analysis

From: Mendelian randomization and transcriptomic analysis reveal an inverse causal relationship between Alzheimer’s disease and cancer

 

Dataset

# SNPs in GWAS

Cases

Controls

Year

AD

ebi-a-GCST005921

7,746,640

42,034

272,244

2018

Cancer

 Endometrial cancer

ebi-a-GCST006465

9,464,330

8758

46,126

2018

ebi-a-GCST006466

8,947,630

1230

35,447

2018

 Follicular lymphoma

finn-b-CD2_FOLLICULAR_LYMPHOMA_EXALLC

16,380,337

522

180,756

2021

 Breast cancer

ieu-a-1126

10,680,257

122,977

105,974

2017

ieu-a-1132

10,680,257

38,197

45,494

2017

ukb-b-12227

9,851,867

16,586

345,223

2018

ukb-b-13584

9,851,867

35,102

388,356

2018

 Prostate cancer

ieu-b-85

20,346,368

79,148

61,106

2018

ukb-b-7773

9,851,867

30,945

368,725

2018

 Oral cavity cancer

ieu-b-94

7,510,833

1223

2928

2016

 Bowel cancer

ukb-a-296

10,894,596

107,072

224,939

2017

ukb-b-7748

9,851,867

22,028

401,107

2018

ukb-b-17001

9,851,867

146,163

309,096

2018