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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Small extracellular vesicles-transported lncRNA TDRKH-AS1 derived from AOPPs-treated trophoblasts initiates endothelial cells pyroptosis through PDIA4/DDIT4 axis in preeclampsia

Fig. 5

TDRKH-AS1 causes pyroptosis in HUVECs. A The detection of expression proteins is observed by confocal microscopy. NLRP3 and GSDMD antibody conjugated with Alexa 594, and nuclei was labeled with DAPI. (× 400; scale bar = 20 µm). B The levels of LDH release in each group. C, D The concentration of IL-1β and IL-18 in different treated HUVECs was detected by ELISA. The data are represented as the mean ± SD; **p < 0.01, *p < 0.05.

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