Table 2 The C-indices of different risk models for the all-cause mortality prediction

C-index (95% CI)

 Overall

  Blood biomarker score

0.71 (0.70–0.71)

0.68 (0.67–0.68)

0.73 (0.72–0.75)

0.70 (0.68–0.73)

  Blood biomarker score plus baseline age

0.74 (0.74–0.75)

0.72 (0.71–0.73)

0.76 (0.75–0.77)

0.76 (0.74–0.78)

  Traditional risk score

0.59 (0.58–0.60)

0.60 (0.59–0.61)

0.60 (0.58–0.62)

0.63 (0.60–0.65)

  Traditional risk score plus baseline age

0.72 (0.71–0.72)

0.71 (0.70–0.72)

0.73 (0.71–0.74)

0.75 (0.73–0.77)

  Combined model^a

0.75 (0.74–0.75)

0.72 (0.72–0.73)

0.76 (0.75–0.78)

0.77 (0.75–0.79)

  P value^b

 < 0.001

 < 0.001

 < 0.001

 < 0.001

Follow-up years^c

  ≤ Median

   Blood biomarker score

0.70 (0.69–0.71)

0.67 (0.66–0.68)

0.72 (0.70–0.74)

0.70 (0.67–0.72)

   Blood biomarker score plus baseline age

0.73 (0.72–0.73)

0.71 (0.70–0.72)

0.75 (0.73–0.76)

0.75 (0.73–0.77)

   Traditional risk score

0.59 (0.58–0.59)

0.60 (0.59–0.61)

0.60 (0.58–0.62)

0.62 (0.60–0.65)

   Traditional risk score plus baseline age

0.69 (0.69–0.70)

0.70 (0.69–0.71)

0.71 (0.70–0.73)

0.74 (0.72–0.76)

  Combined model^a

0.73 (0.72–0.73)

0.71 (0.71–0.72)

0.75 (0.73–0.76)

0.75 (0.73–0.77)

   > Median

   Blood biomarker score

0.72 (0.69–0.74)

0.66 (0.63–0.69)

0.81 (0.73–0.88)

0.70 (0.59–0.81)

   Blood biomarker score plus baseline age

0.75 (0.73–0.77)

0.74 (0.72–0.78)

0.80 (0.71–0.89)

0.73 (0.63–0.84)

   Traditional risk score

0.60 (0.57–0.62)

0.62 (0.58–0.65)

0.58 (0.47–0.69)

0.66 (0.53–0.79)

   Traditional risk score plus baseline age

0.73 (0.71–0.75)

0.75 (0.72–0.78)

0.70 (0.58–0.83)

0.75 (0.67–0.83)

   Combined model^a

0.75 (0.74–0.77)

0.75 (0.72–0.78)

0.80 (0.71–0.89)

0.75 (0.67–0.84)