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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1

Fig. 1

A Changes in the viability of 4T1, MDA-MB-231 and HUEVC cells under different concentrations of DMKG and different radiation doses. B Apoptosis of 4T1 and MDA-MB-231 cells under different interventions, detected by flow cytometry. C DNA damage of 4T1 cells indicated by immunofluorescence staining of γ-H2AX after various treatments. D Intracellular ROS detection in 4T1 cells by DCFH-DA after various treatments. E Fluorescence quantization results of ROS and γH2AX. F Flow cytometry detection of intracellular ROS levels and corresponding quantitative plots. The concentration of DMKG was 10 mM. The radiation dose was 4 Gy. Scale bar was shown in the figure

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