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Table 1 Clinical characteristics of 208 patients in the Fuwai DCM HTx cohort

From: Genetic characterization of dilated cardiomyopathy patients undergoing heart transplantation in the Chinese population by whole-exome sequencing

Characteristics

General

(n = 208)

Male

(n = 167)

Female

(n = 41)

Sex (%)

208 (100)

167 (80.3)

41 (19.7)

Height (cm)

170.2 ± 7.8

172.4 ± 6.6

161.3 ± 5.3

Weight (kg)

63.5 ± 12.0

66.2 ± 11.4

52.7 ± 7.8

BMI (kg/m2)

21.8 ± 3.4

22.2 ± 3.4

20.2 ± 2.9

NTpro-BNP (× 103 ng/L)

2.8 ± 2.2

2.8 ± 2.2

3.0 ± 2.0

Age of onset (years old)

36.5 ± 11.8

36.1 ± 11.7

37.8 ± 11.9

Age of transplantation (years old)

42.4 ± 13.2

42.3 ± 13.0

42.9 ± 14.1

Disease course (month)

71.6 ± 65.6

74.2 ± 66.4

61.2 ± 61.7

Family history, n (%)

18 (8.7)

15 (9.0)

3 (7.3)

AF, n (%)

58 (27.9)

49 (29.3)

9 (22.0)

Pacemaker, n (%)

40 (19.2)

36 (21.6)

4 (9.8)

Diabetes, n (%)

14 (6.7)

11 (6.6)

3 (7.3)

Echocardiography

 

 LAD (mm)

49.7 ± 8.8

51.0 ± 9.0

44.5 ± 5.2

 LVEDD (mm)

75.7 ± 10.8

77.5 ± 10.4

68.4 ± 9.1

 LVEF (%)

23.9 ± 6.4

23.8 ± 6.5

24.2 ± 6.1

 IVS (mm)

8.5 ± 1.4

8.7 ± 1.4

8.0 ± 1.5

 RVD (mm)

27.0 ± 5.9

27.4 ± 5.8

25.2 ± 5.8

NYHA scale, n (%)

 

 NYHA class III

61 (29.3)

48 (28.7)

13 (31.7)

 NYHA class IV

147 (70.7)

119 (71.3)

28 (68.3)

  1. Continuous variables are expressed as the mean ± SD values, and all categorical variables are depicted using relative frequency distributions
  2. Disease course: months from symptom onset to heart transplantation
  3. BMI body mass index, AF atrial fibrillation, LAD left atrial diameter, LVEDD left ventricular end-diastolic dimension, LVEF left ventricular ejection fraction, IVS interventricular septum, RVD right ventricle diameter, NYHA New York Heart Association classification