Fig. 3
From: Ligand-based adoptive T cell targeting CA125 in ovarian cancer
Activation marker detection in our engineered T cells co-cultured with tumor cells. A Flow cytometry detection of CD69 and CD25 expression in CR, CAR, CR + CAR, and NTD groups after co-culture of T cells with ovarian cancer cells SKOV3 and OVCAR3 for 24 h. B Statistical chart of the proportion of CD69 and CD25 double-positive T cells in each group. C Flow cytometry detection of CD107A expression in CR, CAR, CR + CAR, and NTD groups after co-culture of T cells with ovarian cancer cells SKOV3 and OVCAR3 for 4 h; D statistical chart of CD107A positive population in T cells of each group. All data are presented as the mean ± SEM of triplicate experiments. *p < 0.05, **p < 0.01, ***p < 0.001, P > 0.05 labeled as N.S was considered no significance