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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Elevated CHCHD4 orchestrates mitochondrial oxidative phosphorylation to disturb hypoxic pulmonary hypertension

Fig. 4

CHCHD4 affects hypoxia-induced proliferation and migration in PASMCs. A Representative immunoblotting of CHCHD4 in PASMCs incubated with len-CTR or len-CHCHD4 (n = 4). B Wound healing assay of PASMCs in each group (n = 3 independent experiments). C Results of the CCK8 cell viability assay of PASMCs in each group (n = 3 independent experiments). D, E Representative images and summary data of the Transwell assay, which indicated the migration ability of PASMCs in indicated groups (n = 3 independent experiments). F Representative immunoblotting of CHCHD4 in PASMCs incubated with siCTR or siCHCHD4 (n = 4). G Wound healing assay of PASMCs in each group (n = 3 independent experiments). H Results of the CCK8 cell viability assay of PASMCs in each group (n = 3 independent experiments). I, J Representative images and summary data of the Transwell assay, which indicated the migration ability of PASMCs in indicated groups (n = 3 independent experiments). Data are shown as the mean ± SEM. P value is showed in each figure

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