Fig. 5
From: TIMELESS upregulates PD-L1 expression and exerts an immunosuppressive role in breast cancer
TIM affects the tumor migration and invasion ability by regulating PD-L1 expression in breast cancer cell lines. a The migration and invasion analyses in breast cancer TIM knockdown cells. b The migration and invasion analyses in breast cancer TIM overexpression cells. c CCK-8 assay in breast cancer TIM knockdown cells with or without PD-L1 overexpression. d Clonal formation assay in breast cancer TIM knockdown cells with or without PD-L1 overexpression. e The migration and invasion analyses in breast cancer TIM knockdown cells with or without PD-L1 overexpression. Significance was tested using Mann–Whitney U-test: *p-value < 0.05; **p-value < 0.01; ***p-value < 0.001