Fig. 4

Communications between adipocyte subpopulations and immune cells. A UMAP plot showing 9 major immune cell types in mouse VAT. B Dot plot of marker genes for each immune cell types in mouse VAT. C Relative proportions of immune cell types in mouse VAT from HFD mouse (n = 11) or NCD mouse (n = 8). D Heatmap showing the number of the ligand-receptor pairs between each immune cell type and adipocyte subpopulation in mouse VAT. E Circos plot showing the weights/strength of interactions between ligands and receptors across cell types in mouse VAT. The size of nodes denotes the weights/strength of pairs involved in each cell type, and the thickness of the line is proportional to the weights/strength of the pairs between two nodes. F UMAP plot showing 9 major immune cell types in mouse SAT. G Dot plot of marker genes for each immune cell types in mouse VAT. H Relative proportions of immune cell types in mouse SAT from HFD mouse (n = 6) or NCD mouse (n = 22). I Heatmap showing the number of the ligand-receptor pairs between each immune cell type and adipocyte subpopulation in mouse SAT. J Circos plot showing the weights/strength of interactions between ligands and receptors across cell types in mouse SAT. The size of nodes denotes the weights/strength of pairs involved in each cell type, and the thickness of the line is proportional to the weights/strength of the pairs between two nodes