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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

Fig. 4

Infection of putative cancer stem cells of GBM in vitro. a Florescent cell sorting profiles of GBM cells after CD133 and CD15 dual staining. b Florescent and phase contrast images of SVV-GFP infection of the purified CD133 and/or CD15 positive GBM cells in a permissive model (A46GB) as compared with a resistant model (K035GBM). c Quantitative analysis of SVV-GFP infectivity in FACS purified CD133+ and/or CD15+ cells from 3 permissive GBM models and 1 resistant model. *P<0.05; **P<0.01

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