Fig. 2

RNAseq analysis and in vivo tumor growth of PDOX models. a Hierarchical clustering of the top 33 differentially expressed genes in PDOX tumors along with their matching patient tumors. b Heatmap showing comparisons of differentially expressed genes between patient (Pt) and PDOX tumors (Xeno) in three models representing high levels of agreement in K035GBM, middle levels in K024GBM and low levels of K045GBM. c Time course in vivo tumor growth of ICK012GBM. d Log-ranks analysis showing the impact the implanted tumor cells (from 1,000 to 100,000) on the changes of animal survival times