Fig. 2

Distribution of ACE2, ADAM17 and CTSL. A Violin plot and scatterplot of ACE2 expression in different cell types in DCM, ICM, hypertension and healthy myocardial tissue; B ACE2⁺ADAM17⁺, ACE2⁺CTSL⁺ and ACE2⁺-LMAN2⁺ cells in different states and cell types, where blue represents double-positive cells; C Correlation between ACE2⁺ADAM17⁺ and cell type in DCM, ICM, hypertension and healthy myocardial tissue; D Marker genes of different cell types and the expression of ACE2, ADAM17 and CTSL in different cell types; E Volcano plot of the differential analysis of ACE2⁺ADAM17⁺ cells relative to all others; F Violin plot and scatter plot of ACE2, ADAM17 and CTSL expression in different cardiomyocyte subtypes