Fig. 1

The landscape of the cellular composition of the heart from healthy and CVD patients at a single-cell resolution. A UMAP plot showing annotated cardiomyocyte types; B Distribution of each cell type of cardiomyocytes in different disease states; C Proportions of different cell types in the left ventricle (up) and right ventricle (down); D Violin plot generated from the comprehensive dataset showing the signature marker genes for each identified cell population; E Pie chart of the proportions of cardiomyocyte types in different disease states; F UMAP diagram of the proportions of cardiomyocyte types in different disease states