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Table 1 Population and clinical characteristics of patients with gouty arthritis and normal subjects

From: Phospholipase A2 regulates autophagy in gouty arthritis: proteomic and metabolomic studies

 

T (gouty arthritis)

N (normal group)

P value

N

10

10

 

Age(years)

42.3 ± 9.202

38.4 ± 8.884

0.159

Male, gender

100%

80%

0.136

Smoker/non-smoker

10%

0%

0.305

Alcohol consumption (%)

10%

0%

0.305

BMI(kg/m2)

27.35 ± 1.32

22.13 ± 2.33

 < 0.001

Activity limitations

80%

0%

0

Swollen joints1YES, 2NO

100%

0%

0

Arthrohydrops1YES, 2NO

50%

0%

0.051

Diabetes DM

20%

0%

0.136

Hypertension

20%

0%

0.136

C-reactive protein, CRP mg/L (< 5)

17.7 (3.57–87.68)

1.31 (1.06–1.79)

0.000**

Uric acid (240–490) μmol/L

509.4 ± 114.5

316.2 ± 100.9

0.001*

HDL-cholesterol (mmol/L) (> 0.9)

0.99 ± 0.22

1.37 ± 0.25

0.002*

LDL-cholesterol(mmol/L)(< 0.40)

2.83 ± 1.27

2.56 ± 0.73

0.577*

Cholesterol CHO(mmol/L) (2.8–5.7)

4.51 ± 1.60

4.27 ± 0.81

0.684*

Triglyceride TG(mmol/L)(0.29–1.83)

1.7 (1.37–2.60)

0.74 (0.58–2.00)

0.043**

ESR (< 21)

19.5 (6.5–60.75)

7.00 (3.75–13.75)

0.035**

WBC (3.5–9.5)

7.05 ± 2.79

5.39 ± 0.99

0.093*

MO# (0.1–0.6)

0.47 ± 0.22

0.32 ± 0.05

0.059*

LY# (1.1–3.2)

1.37 (1.26–2.11)

2.05 (1.81–2.31)

0.105**

  1. *p-values represent differences among groups as compared by Student’s t-test
  2. **p-values represent differences among groups as compared by the Wilcoxon signed-rank test
  3. ***p-values represent differences among groups as compared by Chi-squared test