Fig. 3

Serum exosomal metabolites as biomarkers to differentiate between remote ischemic preconditioning (RIPC) participants and controls. A ROC curves were utilized to evaluate the accuracy of the analysis of a cluster of 5 metabolites; B A scatter plot of the probability of participants belonging to cases by the 5 metabolites; Boxplot of C ethyl salicylate (P = 1.06E-07); D ethionamide (P = 9.13E-08); E piperic acid (P = 4.54E-09); F 2,6-di-tert-butyl-4-hydroxymethylphenol (P = 8.16E-09); G zerumbone levels (P = 4.23E-10). AUC, area under curve; ROC, receiver operating characteristic