Table 1 The names, IDs, targets, and pathways of the 7 drugs
Drug name | Drug ID | Drug target | Target Pathway | Screening Set |
|---|---|---|---|---|
BMS-754807 | 184 | IGF1R, IR | RTK signaling | GDSC1 |
NU7441 | 1038 | DNAPK | Genome integrity | GDSC1 |
RO-3306 | 1052 | CDK1 | Cell cycle | GDSC1 |
JQ1 | 1218 | BRD2, BRD3, BRD4, BRDT | Chromatin other | GDSC1 |
AZD8186 | 1444 | PI3Kbeta, PI3Kdelta | PI3K/MTOR signaling | GDSC1 |
AZD8055 | 1059 | MTORC1, MTORC2 | PI3K/MTOR signaling | GDSC1 |
SB216763 | 1025 | GSK3A, GSK3B | WNT signaling | GDSC1 |